Isolation and Characterization of a Deoxynivalenol-Degrading Bacterium Bacillus licheniformis YB9 with the Capability of Modulating Intestinal Microbial Flora of Mice.
Identifieur interne : 000151 ( Main/Exploration ); précédent : 000150; suivant : 000152Isolation and Characterization of a Deoxynivalenol-Degrading Bacterium Bacillus licheniformis YB9 with the Capability of Modulating Intestinal Microbial Flora of Mice.
Auteurs : Shiwei Wang [République populaire de Chine] ; Qiuqiu Hou [République populaire de Chine] ; Qianqian Guo [République populaire de Chine] ; Jian Zhang [République populaire de Chine] ; Yanmei Sun [République populaire de Chine] ; Hong Wei [République populaire de Chine] ; Lixin Shen [République populaire de Chine]Source :
- Toxins [ 2072-6651 ] ; 2020.
Abstract
Deoxynivalenol (DON) is one of the most prevalent food- and feed-associated mycotoxins. It frequently contaminates agricultural commodities and poses serious threats to human and animal health and leads to tremendous economic losses globally. Much attention has been paid to using microorganisms to detoxify DON. In this study, a Bacillus licheniformis strain named YB9 with a strong ability to detoxify DON was isolated and characterized from a moldy soil sample. YB9 could degrade more than 82.67% of 1 mg/L DON within 48 h at 37 °C and showed strong survival and DON degradation rate at simulated gastric fluid. The effects of YB9 on mice with DON intragastrical administration were further investigated by biochemical and histopathological examination and the gut microbiota was analyzed by 16S rRNA Illumina sequencing technology. The results showed that DON increased the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and creatinine (Cr), decreased those of immunoglobulin G (IgG) and IgM in serum, and resulted in severe pathological damage of the liver, kidney, and spleen. By contrast, YB9 supplementation obviously inhibited or attenuated the damages caused by DON in mice. In addition, YB9 addition repaired the DON-induced dysbiosis of intestinal flora, characterized by recovering the balance of Firmicutes and Bacteroidetes to the normal level and decreasing the abundance of the potentially harmful bacterium Turicibacter and the excessive Lactobacillus caused by DON. Taken together, DON-degrading strain YB9 might be used as potential probiotic additive for improving food and feed safety and modulating the intestinal microbial flora of humans and animals.
DOI: 10.3390/toxins12030184
PubMed: 32183451
PubMed Central: PMC7150942
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Isolation and Characterization of a Deoxynivalenol-Degrading Bacterium <i>Bacillus licheniformis YB9</i> with the Capability of Modulating Intestinal Microbial Flora of Mice.</title><author><name sortKey="Wang, Shiwei" sort="Wang, Shiwei" uniqKey="Wang S" first="Shiwei" last="Wang">Shiwei Wang</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069</wicri:regionArea><wicri:noRegion>Xi'an 710069</wicri:noRegion></affiliation></author><author><name sortKey="Hou, Qiuqiu" sort="Hou, Qiuqiu" uniqKey="Hou Q" first="Qiuqiu" last="Hou">Qiuqiu Hou</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069</wicri:regionArea><wicri:noRegion>Xi'an 710069</wicri:noRegion></affiliation></author><author><name sortKey="Guo, Qianqian" sort="Guo, Qianqian" uniqKey="Guo Q" first="Qianqian" last="Guo">Qianqian Guo</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069</wicri:regionArea><wicri:noRegion>Xi'an 710069</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Jian" sort="Zhang, Jian" uniqKey="Zhang J" first="Jian" last="Zhang">Jian Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069</wicri:regionArea><wicri:noRegion>Xi'an 710069</wicri:noRegion></affiliation></author><author><name sortKey="Sun, Yanmei" sort="Sun, Yanmei" uniqKey="Sun Y" first="Yanmei" last="Sun">Yanmei Sun</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069</wicri:regionArea><wicri:noRegion>Xi'an 710069</wicri:noRegion></affiliation></author><author><name sortKey="Wei, Hong" sort="Wei, Hong" uniqKey="Wei H" first="Hong" last="Wei">Hong Wei</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Agricultural Microbiology, College of Animal Sciences and Technology, Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of the Ministry of Education & Key Laboratory of Swine Genetics and Breeding of Ministry of Agriculture and Rural Affairs, Huazhong Agricultural University, Wuhan 430070, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory of Agricultural Microbiology, College of Animal Sciences and Technology, Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of the Ministry of Education & Key Laboratory of Swine Genetics and Breeding of Ministry of Agriculture and Rural Affairs, Huazhong Agricultural University, Wuhan 430070</wicri:regionArea><placeName><settlement type="city">Wuhan</settlement><region type="région">Hubei</region></placeName></affiliation></author><author><name sortKey="Shen, Lixin" sort="Shen, Lixin" uniqKey="Shen L" first="Lixin" last="Shen">Lixin Shen</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069</wicri:regionArea><wicri:noRegion>Xi'an 710069</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32183451</idno><idno type="pmid">32183451</idno><idno type="doi">10.3390/toxins12030184</idno><idno type="pmc">PMC7150942</idno><idno type="wicri:Area/Main/Corpus">000167</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000167</idno><idno type="wicri:Area/Main/Curation">000167</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000167</idno><idno type="wicri:Area/Main/Exploration">000167</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Isolation and Characterization of a Deoxynivalenol-Degrading Bacterium <i>Bacillus licheniformis YB9</i> with the Capability of Modulating Intestinal Microbial Flora of Mice.</title><author><name sortKey="Wang, Shiwei" sort="Wang, Shiwei" uniqKey="Wang S" first="Shiwei" last="Wang">Shiwei Wang</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069</wicri:regionArea><wicri:noRegion>Xi'an 710069</wicri:noRegion></affiliation></author><author><name sortKey="Hou, Qiuqiu" sort="Hou, Qiuqiu" uniqKey="Hou Q" first="Qiuqiu" last="Hou">Qiuqiu Hou</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069</wicri:regionArea><wicri:noRegion>Xi'an 710069</wicri:noRegion></affiliation></author><author><name sortKey="Guo, Qianqian" sort="Guo, Qianqian" uniqKey="Guo Q" first="Qianqian" last="Guo">Qianqian Guo</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069</wicri:regionArea><wicri:noRegion>Xi'an 710069</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Jian" sort="Zhang, Jian" uniqKey="Zhang J" first="Jian" last="Zhang">Jian Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069</wicri:regionArea><wicri:noRegion>Xi'an 710069</wicri:noRegion></affiliation></author><author><name sortKey="Sun, Yanmei" sort="Sun, Yanmei" uniqKey="Sun Y" first="Yanmei" last="Sun">Yanmei Sun</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069</wicri:regionArea><wicri:noRegion>Xi'an 710069</wicri:noRegion></affiliation></author><author><name sortKey="Wei, Hong" sort="Wei, Hong" uniqKey="Wei H" first="Hong" last="Wei">Hong Wei</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Agricultural Microbiology, College of Animal Sciences and Technology, Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of the Ministry of Education & Key Laboratory of Swine Genetics and Breeding of Ministry of Agriculture and Rural Affairs, Huazhong Agricultural University, Wuhan 430070, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory of Agricultural Microbiology, College of Animal Sciences and Technology, Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of the Ministry of Education & Key Laboratory of Swine Genetics and Breeding of Ministry of Agriculture and Rural Affairs, Huazhong Agricultural University, Wuhan 430070</wicri:regionArea><placeName><settlement type="city">Wuhan</settlement><region type="région">Hubei</region></placeName></affiliation></author><author><name sortKey="Shen, Lixin" sort="Shen, Lixin" uniqKey="Shen L" first="Lixin" last="Shen">Lixin Shen</name><affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069</wicri:regionArea><wicri:noRegion>Xi'an 710069</wicri:noRegion></affiliation></author></analytic><series><title level="j">Toxins</title><idno type="eISSN">2072-6651</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Deoxynivalenol (DON) is one of the most prevalent food- and feed-associated mycotoxins. It frequently contaminates agricultural commodities and poses serious threats to human and animal health and leads to tremendous economic losses globally. Much attention has been paid to using microorganisms to detoxify DON. In this study, a <i>Bacillus licheniformis</i> strain named YB9 with a strong ability to detoxify DON was isolated and characterized from a moldy soil sample. YB9 could degrade more than 82.67% of 1 mg/L DON within 48 h at 37 °C and showed strong survival and DON degradation rate at simulated gastric fluid. The effects of YB9 on mice with DON intragastrical administration were further investigated by biochemical and histopathological examination and the gut microbiota was analyzed by 16S rRNA Illumina sequencing technology. The results showed that DON increased the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and creatinine (Cr), decreased those of immunoglobulin G (IgG) and IgM in serum, and resulted in severe pathological damage of the liver, kidney, and spleen. By contrast, YB9 supplementation obviously inhibited or attenuated the damages caused by DON in mice. In addition, YB9 addition repaired the DON-induced dysbiosis of intestinal flora, characterized by recovering the balance of Firmicutes and Bacteroidetes to the normal level and decreasing the abundance of the potentially harmful bacterium <i>Turicibacter</i> and the excessive <i>Lactobacillus</i> caused by DON. Taken together, DON-degrading strain YB9 might be used as potential probiotic additive for improving food and feed safety and modulating the intestinal microbial flora of humans and animals.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">32183451</PMID><DateRevised><Year>2020</Year><Month>08</Month><Day>11</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">2072-6651</ISSN><JournalIssue CitedMedium="Internet"><Volume>12</Volume><Issue>3</Issue><PubDate><Year>2020</Year><Month>03</Month><Day>15</Day></PubDate></JournalIssue><Title>Toxins</Title><ISOAbbreviation>Toxins (Basel)</ISOAbbreviation></Journal><ArticleTitle>Isolation and Characterization of a Deoxynivalenol-Degrading Bacterium <i>Bacillus licheniformis YB9</i> with the Capability of Modulating Intestinal Microbial Flora of Mice.</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">E184</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.3390/toxins12030184</ELocationID><Abstract><AbstractText>Deoxynivalenol (DON) is one of the most prevalent food- and feed-associated mycotoxins. It frequently contaminates agricultural commodities and poses serious threats to human and animal health and leads to tremendous economic losses globally. Much attention has been paid to using microorganisms to detoxify DON. In this study, a <i>Bacillus licheniformis</i> strain named YB9 with a strong ability to detoxify DON was isolated and characterized from a moldy soil sample. YB9 could degrade more than 82.67% of 1 mg/L DON within 48 h at 37 °C and showed strong survival and DON degradation rate at simulated gastric fluid. The effects of YB9 on mice with DON intragastrical administration were further investigated by biochemical and histopathological examination and the gut microbiota was analyzed by 16S rRNA Illumina sequencing technology. The results showed that DON increased the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and creatinine (Cr), decreased those of immunoglobulin G (IgG) and IgM in serum, and resulted in severe pathological damage of the liver, kidney, and spleen. By contrast, YB9 supplementation obviously inhibited or attenuated the damages caused by DON in mice. In addition, YB9 addition repaired the DON-induced dysbiosis of intestinal flora, characterized by recovering the balance of Firmicutes and Bacteroidetes to the normal level and decreasing the abundance of the potentially harmful bacterium <i>Turicibacter</i> and the excessive <i>Lactobacillus</i> caused by DON. Taken together, DON-degrading strain YB9 might be used as potential probiotic additive for improving food and feed safety and modulating the intestinal microbial flora of humans and animals.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Shiwei</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hou</LastName><ForeName>Qiuqiu</ForeName><Initials>Q</Initials><AffiliationInfo><Affiliation>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Guo</LastName><ForeName>Qianqian</ForeName><Initials>Q</Initials><AffiliationInfo><Affiliation>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Jian</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sun</LastName><ForeName>Yanmei</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wei</LastName><ForeName>Hong</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>State Key Laboratory of Agricultural Microbiology, College of Animal Sciences and Technology, Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of the Ministry of Education & Key Laboratory of Swine Genetics and Breeding of Ministry of Agriculture and Rural Affairs, Huazhong Agricultural University, Wuhan 430070, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Shen</LastName><ForeName>Lixin</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>81770434, 31770152, and 31400094</GrantID><Agency>National Natural Science Foundation of China</Agency><Country>International</Country></Grant><Grant><GrantID>2018ZDXM-SF-004</GrantID><Agency>he Provincial Natural Science Foundation of Shaanxi Province</Agency><Country>International</Country></Grant><Grant><GrantID>2017YFD0500503 and 2017YFD0501000</GrantID><Agency>Chinese National key R & D projects</Agency><Country>International</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>03</Month><Day>15</Day></ArticleDate></Article><MedlineJournalInfo><Country>Switzerland</Country><MedlineTA>Toxins (Basel)</MedlineTA><NlmUniqueID>101530765</NlmUniqueID><ISSNLinking>2072-6651</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">Bacillus licheniformis YB9</Keyword><Keyword MajorTopicYN="Y">degradation and detoxification</Keyword><Keyword MajorTopicYN="Y">deoxynivalenol</Keyword><Keyword MajorTopicYN="Y">intestinal microbial flora</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>02</Month><Day>18</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2020</Year><Month>03</Month><Day>06</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>03</Month><Day>11</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>3</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>3</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>3</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32183451</ArticleId><ArticleId IdType="pii">toxins12030184</ArticleId><ArticleId IdType="doi">10.3390/toxins12030184</ArticleId><ArticleId IdType="pmc">PMC7150942</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Toxins (Basel). 2013 Apr 29;5(5):912-25</Citation><ArticleIdList><ArticleId IdType="pubmed">23628787</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2018 Dec 17;13(12):e0207745</Citation><ArticleIdList><ArticleId IdType="pubmed">30557387</ArticleId></ArticleIdList></Reference><Reference><Citation>Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2017 Jan;34(1):103-112</Citation><ArticleIdList><ArticleId IdType="pubmed">27796167</ArticleId></ArticleIdList></Reference><Reference><Citation>Rapid Commun Mass Spectrom. 2006;20(5):771-6</Citation><ArticleIdList><ArticleId IdType="pubmed">16470672</ArticleId></ArticleIdList></Reference><Reference><Citation>Arch Toxicol. 2016 Dec;90(12):2931-2957</Citation><ArticleIdList><ArticleId IdType="pubmed">27663890</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2018 Apr 11;13(4):e0194866</Citation><ArticleIdList><ArticleId IdType="pubmed">29641608</ArticleId></ArticleIdList></Reference><Reference><Citation>J Vet Sci. 2008 Sep;9(3):257-66</Citation><ArticleIdList><ArticleId IdType="pubmed">18716445</ArticleId></ArticleIdList></Reference><Reference><Citation>Food Res Int. 2019 Dec;126:108595</Citation><ArticleIdList><ArticleId IdType="pubmed">31732076</ArticleId></ArticleIdList></Reference><Reference><Citation>J Appl Microbiol. 2019 Sep;127(3):880-888</Citation><ArticleIdList><ArticleId IdType="pubmed">31211897</ArticleId></ArticleIdList></Reference><Reference><Citation>BMC Vet Res. 2015 Jul 03;11:144</Citation><ArticleIdList><ArticleId IdType="pubmed">26138080</ArticleId></ArticleIdList></Reference><Reference><Citation>Biosci Biotechnol Biochem. 2006 Jul;70(7):1764-8</Citation><ArticleIdList><ArticleId IdType="pubmed">16861811</ArticleId></ArticleIdList></Reference><Reference><Citation>Biol Pharm Bull. 2007 Sep;30(9):1808-12</Citation><ArticleIdList><ArticleId IdType="pubmed">17827746</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Gastroenterol. 2010 Sep;44 Suppl 1:S30-4</Citation><ArticleIdList><ArticleId IdType="pubmed">20697291</ArticleId></ArticleIdList></Reference><Reference><Citation>Environ Toxicol Pharmacol. 2015 Nov;40(3):686-91</Citation><ArticleIdList><ArticleId IdType="pubmed">26407231</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicon. 2017 Jan;125:32-43</Citation><ArticleIdList><ArticleId IdType="pubmed">27840141</ArticleId></ArticleIdList></Reference><Reference><Citation>Mycotoxin Res. 2017 Feb;33(1):25-37</Citation><ArticleIdList><ArticleId IdType="pubmed">27817099</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicol Lett. 2004 Oct 10;153(1):61-73</Citation><ArticleIdList><ArticleId IdType="pubmed">15342082</ArticleId></ArticleIdList></Reference><Reference><Citation>Environ Toxicol Pharmacol. 2015 Jan;39(1):339-46</Citation><ArticleIdList><ArticleId IdType="pubmed">25553575</ArticleId></ArticleIdList></Reference><Reference><Citation>Food Chem Toxicol. 2016 Jun;92:143-9</Citation><ArticleIdList><ArticleId IdType="pubmed">27016490</ArticleId></ArticleIdList></Reference><Reference><Citation>World J Microbiol Biotechnol. 2012 Jan;28(1):7-13</Citation><ArticleIdList><ArticleId IdType="pubmed">22806774</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxins (Basel). 2016 Oct 25;8(11):</Citation><ArticleIdList><ArticleId IdType="pubmed">27792137</ArticleId></ArticleIdList></Reference><Reference><Citation>Int J Mol Sci. 2009 Jan;10(1):1-17</Citation><ArticleIdList><ArticleId IdType="pubmed">19333431</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicol Lett. 2008 May 5;178(2):83-7</Citation><ArticleIdList><ArticleId IdType="pubmed">18395371</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxins (Basel). 2018 Mar 07;10(3):</Citation><ArticleIdList><ArticleId IdType="pubmed">29518941</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicon. 2018 Dec 1;155:9-20</Citation><ArticleIdList><ArticleId IdType="pubmed">30267721</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicol Appl Pharmacol. 2019 Jun 1;372:47-56</Citation><ArticleIdList><ArticleId IdType="pubmed">30981666</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxins (Basel). 2017 Nov 27;9(12):</Citation><ArticleIdList><ArticleId IdType="pubmed">29186895</ArticleId></ArticleIdList></Reference><Reference><Citation>Genome Announc. 2017 Mar 16;5(11):</Citation><ArticleIdList><ArticleId IdType="pubmed">28302773</ArticleId></ArticleIdList></Reference><Reference><Citation>J Appl Toxicol. 2017 May;37(5):518-529</Citation><ArticleIdList><ArticleId IdType="pubmed">27996102</ArticleId></ArticleIdList></Reference><Reference><Citation>Lett Appl Microbiol. 2017 Nov;65(5):414-422</Citation><ArticleIdList><ArticleId IdType="pubmed">28799167</ArticleId></ArticleIdList></Reference><Reference><Citation>Molecules. 2017 Apr 26;22(5):</Citation><ArticleIdList><ArticleId IdType="pubmed">28445424</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxins (Basel). 2017 Oct 20;9(10):</Citation><ArticleIdList><ArticleId IdType="pubmed">29053594</ArticleId></ArticleIdList></Reference><Reference><Citation>Chemosphere. 2017 Aug;180:267-274</Citation><ArticleIdList><ArticleId IdType="pubmed">28411543</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicol Lett. 2015 Feb 3;232(3):601-11</Citation><ArticleIdList><ArticleId IdType="pubmed">25549547</ArticleId></ArticleIdList></Reference><Reference><Citation>Acta Pharm Sin B. 2015 Jan;5(1):38-46</Citation><ArticleIdList><ArticleId IdType="pubmed">26579423</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxins (Basel). 2017 Apr 07;9(4):</Citation><ArticleIdList><ArticleId IdType="pubmed">28387743</ArticleId></ArticleIdList></Reference><Reference><Citation>Toxicol Appl Pharmacol. 2019 Jul 1;374:20-31</Citation><ArticleIdList><ArticleId IdType="pubmed">31034930</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>République populaire de Chine</li></country><region><li>Hubei</li></region><settlement><li>Wuhan</li></settlement></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Wang, Shiwei" sort="Wang, Shiwei" uniqKey="Wang S" first="Shiwei" last="Wang">Shiwei Wang</name></noRegion><name sortKey="Guo, Qianqian" sort="Guo, Qianqian" uniqKey="Guo Q" first="Qianqian" last="Guo">Qianqian Guo</name><name sortKey="Hou, Qiuqiu" sort="Hou, Qiuqiu" uniqKey="Hou Q" first="Qiuqiu" last="Hou">Qiuqiu Hou</name><name sortKey="Shen, Lixin" sort="Shen, Lixin" uniqKey="Shen L" first="Lixin" last="Shen">Lixin Shen</name><name sortKey="Sun, Yanmei" sort="Sun, Yanmei" uniqKey="Sun Y" first="Yanmei" last="Sun">Yanmei Sun</name><name sortKey="Wei, Hong" sort="Wei, Hong" uniqKey="Wei H" first="Hong" last="Wei">Hong Wei</name><name sortKey="Zhang, Jian" sort="Zhang, Jian" uniqKey="Zhang J" first="Jian" last="Zhang">Jian Zhang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Bois/explor/DetoxFungiV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000151 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000151 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Bois
|area= DetoxFungiV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:32183451
|texte= Isolation and Characterization of a Deoxynivalenol-Degrading Bacterium Bacillus licheniformis YB9 with the Capability of Modulating Intestinal Microbial Flora of Mice.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:32183451" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a DetoxFungiV1
| This area was generated with Dilib version V0.6.38. |  |